Table 5.
Clinical characteristics of the patients with a severe condition of COVID-19
| Characteristics | COVID-19/TBN = 38 (%) | COVID-19N = 36 (%) | p-value |
|---|---|---|---|
| Gender (male/female) | 21 (55,3)/ 17 (44,7) | 22 (61,1)/ 14 (38,9) | 0,610 |
| Contact with COVID-19 | 11 (28,9) | 2 (5,6) | 0,013 |
| Сigarette smoking | 22 (57,9) | 13 (36,1) | 0,061 |
| Signs and Symptoms | |||
| Fever > 38°C | 32 (84,2) | 36 (100,0) | 0,025 |
| Nasal congestion | 3 (7,9) | 20 (55,6) | < 0,001 |
| Fatigue | 12 (31,6) | 23 (63,9) | 0,005 |
| Dyspnea during physical exertion | 22 (57,9) | 23 (63,9) | 0,598 |
| Cough | 27 (71,1) | 35 (97,2) | 0,003 |
| Chest pain | 6 (15,8) | 13 (36,1) | 0,063 |
| Congestion in the chest | 0 (0,0) | 16 (44,4) | < 0,001 |
| Sore throat | 1 (2,6) | 18 (51,4) | < 0,001 |
| Headache | 4 (10,5) | 10 (27,8) | 0,077 |
| Taste disorders | 1 (2,6) | 13 (36,1) | < 0,001 |
| Olfactory disorders | 1 (2,6) | 19 (52,8) | < 0,001 |
| General malaise | 32 (84,2) | 34 (94,4) | 0,263 |
| Rhinorrhea | 0 (0,0) | 1 (2,8) | 0,486 |
| Complications | |||
| DVT/PE (Deep Vein Thrombosis /Pulmonary Embolism) | 1 (2,6) | 13 (36,1) | < 0,001 |
| ARDS (Acute Respiratory Distress Syndrome) | 6 (15,8) | 16 (44,4) | 0,007 |
| Respiratory failure | 17 (44,7) | 30 (83,3) | < 0,001 |
| Sepsis | 0 (0,0) | 6 (16,7) | 0,011 |
| Respiration rate | 23 (22–28) | 22 (20–26) | 0,645 |
| SpO2 | 95 (91–97) | 95 (94–97) | 0,582 |
| Serum CRP | 63 (22–133) | 47 (19–106) | 0,523 |
| CT | |||
| КТ1 | 8 (21.0) | 8 (22.3) | < 0,001 |
| КТ2 | 17 (44,7) | 10 (27,7) | |
| КТ3 | 13(34,3) | 7 (19,5) | |
| КТ4 | 0 (0.0) | 11 (30.5) |