FIGURE 3.

Distinctive intimal Ca²⁺ signaling pattern associated with atherosclerosis (A) Ca²⁺ signaling profiles of arteries from nCVD patients verses CVD patients. The middle panel shows overlapping distributions of parameters (amplitude, duration and area) and the bottom panel shows the difference between the CVD and nCVD distributions (B) Three-dimensional plots show x-y fields of Ca²⁺ signals projected over time for representative CVD and nCVD artery segments. Colors show relative event positions along the y-axis. Data were acquired from three nCVD and four CVD tissue samples. Asterisks (*) indicate p < 0.05.