Figure 5.

Effect of SCS on gut metabolites in tumor-bearing mice. Principal component analysis (PCA) was used to evaluate the differences of gut metabolite composition in each group (A). Heat map of significantly altered fecal metabolites (B), and the Pearson correlation coefficient value R is between −1 and +1. The correlation coefficient R between metabolites is expressed in color and circle, where R > 0 indicates positive correlation and red indicates positive correlation. R < 0 indicates negative correlation, expressed in blue; The larger the circle and the darker the color, the stronger the correlation. Correlation Clustering matrix of significant difference metabolites in each group (C). Enriched KEGG pathway analysis for High group vs. Model group (D).