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. 2022 Mar 17;13(2):e03798-21. doi: 10.1128/mbio.03798-21

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Copyright © 2022 Lechmere et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 3 — Neutralization of omicron in BTI and delta-infected individuals. (A) Schematic showing mutations in the Delta (B.1.617.2) and Omicron (B.1.1.529) spikes. (B and C) Select sera from (B) SARS-CoV-2 Delta-infected (vaccine-naive) individuals (n = 14, 13 to 22 days POS) and (C) BTI individuals (n = 15, 12 to 21 days POS) were tested against WT, Delta, and Omicron VOCs. The ID₅₀ of neutralization against WT (black) and VOCs Delta (purple), and Omicron (turquoise) for each participant are linked. Geometric mean titers against WT, Delta, and Omicron VOCs are shown in red. The GMT and fold decrease in GMT against omicron compared to WT and delta are shown above. Neutralization assays were carried out in duplicate.