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. 2022 Mar 21;13(2):e02759-21. doi: 10.1128/mbio.02759-21

TABLE 1.

Clinical characteristics and outcomes following collection of the index CRAb isolate from each patient

Characteristic Value (n = 120)a
Median age at culture (IQRb) 61 (51–70)
Gender
    Male 72 (60)
    Female 48 (40)
Race
    White 74 (62)
    Black 33 (28)
    Other 7 (6)
    Unknown 6 (5)
Median CCI (IQR)c 3 (1–4)
Median Pitt bacteremia score (IQR)d 3 (2–6)
Admission type
    Admission from home 37 (31)
    Transfer from other hospital 21 (18)
    Transfer from long-term chronic care facility 49 (41)
    Transfer from long-term acute care 13 (11)
Study site
    Cleveland Clinic Foundation 66 (55)
    University of North Carolina at Chapel Hill 3 (3)
    University of Pittsburgh Medical Center 27 (23)
    University of Texas Hospitals 24 (20)
Culture
    Respiratory infection 33 (28)
    Respiratory colonization 23 (19)
    Wound infection 20 (17)
    Wound colonization 23 (19)
    Blood infection 9 (8)
    Urine infection 3 (3)
    Urine colonization 6 (5)
    Other colonization 2 (2)
    Nonwound abdominal infection 1 (1)
DOOR category at 30 dayse
    Alive without events 53 (44)
    Aline with one event 23 (19)
    Alive with two or three events 15 (13)
    Dead 29 (24)
DOOR event at 30 days
    Dead or discharged to hospice 24 (20)
    No clinical response 41 (34)
    Renal failure 8 (7)
    C. difficile infection 3 (3)
Mortality
    30 days 29 (24)
    90 days 32 (27)
Mortality among subjects with infection
    30 days 17 (26)
    90 days 17 (26)
Readmission at 90 days 51 (54)
Readmission at 90 days among subjects with infection 25 (38)
a

Data are number (%) unless stated otherwise.

b

IQR, interquartile range.

c

Charlson comorbidity index (CCI) is a chronic comorbidity score with a range from 0 to 37, with higher scores indicating more comorbid conditions present. A patient with a score of 3 could have three level 1 comorbid conditions (e.g., dementia, chronic pulmonary disease, and congestive heart failure), one level 1 condition (e.g., dementia) and one level 2 condition (e.g., leukemia), or one level 3 condition (moderate or severe liver disease).

d

Pitt bacteremia score is an acute severity of illness score. Higher scores indicate more severe illness. A patient with a score of 3 would have one level 1 marker of acute illness (e.g., disoriented mental state) and one level 2 marker (e.g., hypotension).

e

DOOR (desirability of outcome ranking) analysis components are defined in Materials and Methods.