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Correlation of Gpr41 and microbial carbohydrate metabolism. (A) Relative expression of Gpr41 and Gpr43 in the colons of young versus old mice. (B) Correlation of colonic Gpr41 expression with carbohydrate degradation and fermentation pathways. Significantly correlated pathways are highlighted in red text. (C and D) Comparison of IL-6 and TNF-α in young versus old mice. (C) Colonic Il-6 and Tnfα expression; (D) serum IL-6 and TNF-α. ns, not significant; *, P < 0.05; **, P < 0.01.
