FIG 6.

Early interferon signaling and cytokine/chemokine expression in hamsters treated with active TIPs. Hamsters inoculated i.n. with 100 μL DMEM containing 10⁶ TCID₅₀ NiV strain Malaysia in combination with either 1 × 10⁸ active TIPs (treated with 100 mJ/cm² of UV) or no TIPs (mock treated) were euthanized at 1 or 4 dpi (n = 5 each group). Lung tissues were collected for mRNA analysis. Heatmaps represent fold changes in transcript levels (compared to mock-treated hamsters at each day) of mRNA associated with genes from interferon induction and signaling or cytokine and chemokine signaling pathways. Intensity of color corresponds to magnitude of fold change over baseline.