TABLE 2.
Severe laboratory abnormalities
| Abnormality | No. of patients in the following treatment groupsa:
|
||
|---|---|---|---|
| Intravenous (n = 17) | Oral once daily (n = 6) | Oral twice daily (n = 5) | |
| Biochemistry | |||
| Calcium | 6↓ | 1↓ | 1↓ |
| Chloride | 3↑, 1↓ | 1↑b | |
| Phosphorus | 2↓, 1 | 2↓ | |
| Potassium | 1↓ | 1↓ | |
| Total protein | 4↓ | 2↓ | |
| Albumin | 1↓ | 1↓ | |
| Glucose | 3↑ | 2↑ | |
| Total cholesterol | 1↓ | ||
| Triglycerides | 1↑ | ||
| Total bilirubin | 1↑ | 3↑ | |
| Gamma-glutamyltransferase | 3↑ | 1↑ | |
| AST | 1↑ | ||
| ALT | 2↑ | 1↑ | |
| Urea | 3↑, 1↓ | 1↑ | |
| Uric acid | 2↓ | 1↓ | |
| Hematology | |||
| Hemoglobin | 3↓ | 1↓ | |
| Erythrocyte count | 3↓ | 1↓ | |
| Hematocrit | 3↓ | ||
| Leukocyte count | 7↓c, 1↑, 1↑+↓ | 3↓ | |
| Platelet count | 2↓ | 2↓ | |
Data are numbers of patients with code 4 or code 5 changes. ↑, increase; ↓, decrease.
Code 5 abnormality.
Five patients had code 5 abnormalities.