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. 2022 Feb 11;11(8):1860–1868. doi: 10.1002/cam4.4574

TABLE 5.

Sensitivity and specificity of DNA‐ICM for lung cancer based on a literature review

First author Year No. of patients Specimen type Sensitivity Specificity
Marek W 29 1999 142 patients with suspected lung cancer and 50 controls (COPD, asthma) BW 90% 84%
Schramm M 6 2011 179 patients with suspected lung cancer BW/BB/TBNA 79.0% 98.2%
Tao W 30 2016 216 lung cancer patients, 209 benign lung diseases patients BALF/BB 69.2% 100%
Shi A 23 2018 386 suspected lung cancer patients BALF 69.05% 80.28%

Abbreviations: BALF, bronchial alveolar lavage fluid; BB, bronchial brushing; BW, bronchial washing; TBNA, transbronchial needle aspiration.