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. 2021 Sep 21;11(49):31098–31123. doi: 10.1039/d1ra04480j

Production and purification parameters for 44gSc.

Radioisotope 44gSc
Target material Natural and enriched calcium, enriched calcium carbonate
Product purity >95%
Major impurities 44mSc, 47Sc, 48Sc, 43Sc, 46Sc
Separation method 1 Ion exchange chromatography (UTEVA extraction resin)
- Target dissolution: concentrated HCl
- Ca elution: 10 M HCl
- Sc elution: water
Product separation yield 80%
Target recovery yield
Separation method 2 Ion exchange chromatography (Chelex 100 resin)
- Target dissolution: 0.1 M HCl
- Sc elution: 0.01 M HCl
- Ca elution: 1 M HCl
Product separation yield 70%
Target recovery yield 60%