Table 3.
Accuracy of CapitalBio Mycobacterium RT-PCR Assay, Xpert MTB/RIF, and Parallel Test for Tuberculous Pericarditis Compared with Culture Using Pericardial Fluid
| Test | MTB Culture | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | AUC | ||
|---|---|---|---|---|---|---|---|---|
| Positive | Negative | |||||||
| CapitalBio assay | Positive | 9 | 5 | 50.0 (26.0–74.0) | 91.1 (80.4–97.0) | 64.3 (35.1–87.2) | 85.0 (73.4–92.9) | 0.71 (0.59–0.81) |
| Negative | 9 | 56 | ||||||
| Xpert MTB/RIF | Positive | 11 | 5 | 61.1 (35.8–82.7) | 91.1 (80.4–97.0) | 68.8 (41.3–89.0) | 87.9 (76.7–95.0) | 0.76 (0.65–0.85) |
| Negative | 7 | 56 | ||||||
| Parallel test | Positive | 13 | 5 | 72.2 (46.5–90.3) | 91.1 (80.4–97.0) | 72.2 (46.5–90.3) | 91.1 (80.4–97.0) | 0.82 (0.71–0.90) |
| Negative | 5 | 56 | ||||||
Abbreviations: MTB, Mycobacterium tuberculosis; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the curve.