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. 2022 Apr 22;16:1159–1170. doi: 10.2147/DDDT.S343978

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© 2022 Riaz et al.

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Effects of carvacrol treatment on the inflammatory mediators of PO-induced hyperuricemic rats. The tissue levels of (A) NLRP3 and (B) TNF-α were quantified using ELISA (n = 7 per group). The data are presented as means ± SEM. Representative images showing the immunoreactivity of (C) TNF-α (D) p-NF-κB (n = 7 per group). Scale bar = 50 μm, 40× magnification. The data are presented as means ± SEM. ***p < 0.001 compared to the model group (PO treated), ^###p < 0.001 compared to the saline group, ^##p < 0.01 compared to the saline group, *p < 0.05 compared to the model group (PO treated).