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. 2022 Apr 22;15:2067–2090. doi: 10.2147/IDR.S362099

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© 2022 Nava-Pérez et al.

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Immune response against Sporothrix globosa. Pathogen components trigger an innate immune response via dectin-1, TLR-2 and TLR-4 receptors, and macrophages and mast cells (MCs); an adaptative immune response via dendritic cells (DCs) and Tregs lymphocytes; and a humoral immune response by IgG antibodies. These responses have been observed in either Sporothrix schenckii or Sporothrix brasiliensis and are suggested for S. globosa, except those marked with*, which have already been demonstrated in S. globosa.