7-alpha-HSDH |
7-alpha-hydroxysteroid dehydrogenase |
AA |
arachidonic acid |
AdA |
adrenic acid |
AIH |
autoimmune hepatitis |
ALA |
α-linolenic acid |
ALOX |
arachidonic acid lipoxygenase |
ALP |
alkaline phosphatase |
ALT |
alanine aminotransferase |
ANOVA |
analysis of Variance |
Asp |
Aspartic acid |
AST |
aspartate aminotransferase |
AUC |
area Under Curve |
BAAT |
BA-CoA amino acid N-acyltransferase |
BA |
bile acid |
BSEP |
bile salt export pump |
BSH |
bile salt hydrolase |
CA |
cholic acid |
CDCA |
chenodeoxycholic Acid |
CHB |
chronic hepatitis B |
COX |
cyclooxygenase |
CYP |
cytochrome P450 |
DB |
direct bilirubin |
DCA |
deoxycholic acid |
DHA |
docosahexaenoic acid |
DILI |
drug induced liver injury |
DPA |
docosapentaenoic acid |
EDTA |
ethylene diamine tetraacetic acid |
ELOVL |
elongation of very long chain fatty acids protein |
EPA |
eicosapentaenoic acid |
FADS |
fatty acid desaturase |
FGF19 |
fibroblast growth factor 19 |
FXR |
farnesoid X receptor |
GCA |
glycocholic acid |
GCDCA |
glycochenodeoxycholic acid |
GDCA |
glycodeoxycholic acid |
GLA |
gamma-linolenic acid |
GSH-Px |
glutathione peroxidase |
HCs |
healthy controls |
HHT |
hereditary hemorrhagic telangiectasia |
KEGG |
kyoto encyclopedia of genes and genomes |
LA |
linoleic acid |
LAB |
lactic acid bacteria |
LCA |
lithocholic acid |
LEfSe |
linear discriminant analysis effect size |
LTA4 |
leukotriene A4 |
MDA |
malondialdehyde |
NAFLD |
nonalcoholic fatty liver disease |
NTCP |
sodium-BA cotransporter |
OATP1B1 |
organic anion transporting polypeptide 1B1 |
OATP1B3 |
organic anion transporting polypeptide 1B3 |
OTU |
operational taxonomic unit |
PCA |
principal component analysis |
PGD2 |
prostaglandin D2 |
PGG2 |
prostaglandin G2 |
PGH2 |
prostaglandin H2 |
PLA2G12A |
phospholipase A2 |
group XIIA |
PLA2G4A |
phospholipase A2 |
group IVA |
PLB1 |
phospholipase B1 |
PTGDS |
prostaglandin D2 synthase |
PTGES3 |
prostaglandin E synthase 3 |
PUFA |
polyunsaturated fatty acid |
RF |
random forest |
ROC |
receiver operating characteristic |
ROS |
reactive oxygen species |
SCFA |
short chain fatty acids |
SMPDB |
small molecule pathway database |
TB |
total bilirubin |
TBXAS1 |
thromboxane synthase 1 |
TCA |
taurocholic acid |
TCDCA |
taurochenodeoxycholic acid |
TDCA |
taurodeoxycholate acid |
TUDCA |
tauroursodeoxycholic acid |
TXA2 |
thromboxane A2 |
UDCA |
ursodeoxycholic acid |
GLA |
gamma linolenic acid. |