Table 3. Longitudinal changes in erosion parameters for patients with RA (n = 26).
| (1) Baseline | (2) Follow-up | ||||
|---|---|---|---|---|---|
| Total number of erosions | 34 | 37 | |||
| MCH: 23; PB: 11 | MCH: 26; PB: 11 | ||||
| (new: 4; complete repair: 1) | |||||
| Changes of each erosion | Difference (2)-(1) | ||||
| n | Median (IQR) | Median (IQR) | Median (IQR) | p-value | |
| Er.V (mm3) | Total | 1.67 (0.63, 5.79) | 2.15 (0.85, 6.23) | -0.03 (-0.51, 0.21) | 0.61 |
| Progression: 10 | 0.67 (0.12, 1.97) | 2.45 (1.13, 5.63) | 0.62 (0.42, 0.95) | ||
| Repair: 13 | 5.74 (1.77, 10.4) | 4.88 (0.86, 8.80) | -0.85 (-1.66, -0.57) | ||
| Er.D (mm) | Total | 1.06 (0.85, 1.85) | 1.15 (0.79, 1.78) | -0.03 (-0.12, 0.06) | 0.73 |
| Progression: 7 | 0.00 (0.00, 0.67) | 1.28 (0.94, 1.75) | 0.61 (0.28, 1.52) | ||
| Repair: 9 | 1.82 (1.34, 2.06) | 1.46 (0.73, 1.70) | -0.36 (-0.36, -0.24) | ||
| Er.D-2 (mm) | Total | 1.12 (0.79, 1.93) | 1.21 (0.76, 1.96) | 0.00 (-0.23, 0.12) | 0.86 |
| Progression: 8 | 0.15 (0.00, 0.83) | 1.52 (0.91, 1.87) | 0.43 (0.29, 1.35) | ||
| Repair: 12 | 1.28 (0.96, 2.11) | 0.94 (0.73, 1.78) | -0.39 (-0.55, -0.29) | ||
| Er.W (mm) | Total | 1.79 (1.20, 3.04) | 1.94 (1.34, 3.00) | 0.03 (-0.18, 0.24) | 0.47 |
| Progression: 11 | 1.28 (0.00, 2.12) | 2.19 (1.67, 2.94) | 0.43 (0.30, 1.24) | ||
| Repair: 6 | 2.19 (1.59, 2.96) | 1.58 (1.11, 2.55) | -0.61 (-0.94, -0.46) | ||
| Er.L (mm) | Total | 1.58 (1.26, 2.19) | 1.73 (1.33, 2.79) | 0.06 (-0.17, 0.30) | 0.52 |
| Progression: 14 | 1.24 (0.24, 2.00) | 1.94 (1.52, 3.43) | 0.39 (0.30, 1.05) | ||
| Repair: 10 | 2.55 (1.67, 4.84) | 1.73 (1.27, 3.29) | -0.36 (-1.18, -0.24) | ||
| Er.BMD (mg/cm3) | Total | 329.8 (242.1, 387.6) | 337.1 (285.9, 402.0) | 10.3 (-9.7, 38.1) | 0.39 |
| Increasing: 14 | 249.5 (230.8, 277.7) | 315.4 (269.2, 362.5) | 60.2 (29.2, 88.1) | ||
| Decreasing: 8 | 410.0 (367.3, 473.7) | 378.6 (335.2, 417.5) | -36.5 (-51.0, -26.7) | ||
Values at baseline and follow-up, and differences between them are displayed as median and interquartile range (IQR).
The Wilcoxon signed-rank test was used for comparisons of each value between baseline and follow-up (significant p < 0.05).
Erosions with new occurrence and complete repair were excluded from statistics regarding Er.BMD.
MCH, metacarpal heads; PB, phalangeal bases; Er.V, erosion volume; Er.D, erosion depth in the axial view; Er.D-2, erosion depth in the perpendicular (coronal or sagittal) view; Er.W, erosion width in the axial view; Er.L, erosion length in the perpendicular view; Er.BMD, peripheral bone mineral density surrounding erosion.