Table 1. Physicochemical properties and number of assays and cell lines used for validation of anti-cancer capability of studied peptides.
Peptide Name | Peptide Length | Molecular weight (g/mol) | pH(I)* | Charge at pH 7 | No. of Assays | No. of Cell lines | Water solubility |
---|---|---|---|---|---|---|---|
FLAK93 | 5 aa | 720.9 | 10.69 | +2 | 33 | 117 | Good |
FLAK50T1 | 10 aa | 1102.41 | 10.98 | +3 | 16 | 96 | Good |
FLAK50T6 | 11 aa | 1230.58 | 11.15 | +4 | 11 | 66 | Good |
FLAK94 | 7 aa | 732.91 | 9.88 | +1 | 11 | 65 | Poor |
C-10 | 13 aa | 1713.16 | 11.28 | +5.1 | 7 | 21 | Good |
Tat | 9 aa | 1339.61 | 12.81 | +8 | 6 | 6 | Good |
FLAK50 Z1 | 13 aa | 1344.69 | 11.15 | +4 | 4 | 24 | Good |
LfcinB | 12 aa | 1753.16 | 11.9 | +5.9 | 4 | 20 | Good |
Temporin-La | 13 aa | 1624.02 | 10.26 | +2.1 | 2 | 18 | Good |
LL-37(17–29) | 13 aa | 1719.09 | 11.87 | +4 | 5 | 13 | Good |
GA-K4 | 11 aa | 1494.86 | 11.15 | +4 | 1 | 9 | Good |
Cationic Amphiphilic | 11 aa | 1872.33 | 11.16 | +4 | 3 | 6 | Good |
FLAK-120G | 11 aa | 1167.53 | 10.99 | +3 | 2 | 8 | Good |
Halictine 1 | 12 aa | 1410.73 | 11.41 | +2.1 | 2 | 4 | Poor |
(HHPHG)2 | 10 aa | 1149.18 | 7.97 | +0.6 | 3 | 3 | Poor |
17 | 16 aa | 1698.19 | 11.16 | +4 | 1 | 9 | Poor |
CAME-15 | 15 aa | 1771.28 | 11.28 | +5 | 1 | 10 | Good |
RGD-La | 16 aa | 1952.35 | 10.18 | +2.1 | 1 | 9 | Good |
Retro | 16 aa | 1615.95 | 9.93 | +1 | 1 | 9 | Poor |