Table 2.

Four-point (Designs 1–7) and two-point (Design 8) reflection designs used for fluoranthene [18] simulation study.

Design	Description	Design Points
1 (original)	Original design chosen	$x=5,10,20,30$ for (algae) curves A and B
2 (R/D)	D-optimal design ( $\alpha =1/3$)	$x=11.89,13.85,19.69,22.92$ for curves A and B
3 (R/ $D(0.7)$)	$D_{\alpha }$-optimal design ( $\alpha =0.7$)	$x=12.99,15.13,18.03,20.99$ for curves A and B
4 (R/geom.)	Geometric design (4 points)	$x=11.62,14.69,18.56,23.47$ for curves A and B
5 (R/uniform)	Uniform design (4 points)	$x=11.45,15.27,19.09,22.90$ for curves A and B
6 (R/slope4)	4-parameter D-optimal (slope)	$x=11.13,12.96,21.04,24.49$ for curves A and B
7 (R/scale4)	4-parameter D-optimal (scale)	$x=10.53,14.94,18.25,25.89$ for curves A and B
8 (R/SC2point)	Same-concentration D-opt.	$x=12.76,21.37$ for curves A and B