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. 2022 Apr 26;11:e74293. doi: 10.7554/eLife.74293

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© 2022, Tinnermann et al

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Figure 3. — Spinal regions that show a significant reduction in activity during remifentanil treatment comprise the left dorsal horn (DH) and layer X (LX). Parameter estimates show that spinal activity in the DH is reduced during remifentanil treatment compared to saline. Region of interest (ROI)-masked statistical t-maps are overlaid on an average mean echo planar imaging (EPI) image in PAM50 template space and the visualization threshold is set to p_corr<0.05, which is indicated as a dashed line in the color bar. The dashed circle indicates the cluster from which peak voxel parameter estimates are plotted. Error bars represent standard error of the mean.

Figure 3—figure supplement 1. — Spinal regions that show a significant reduction in activity during remifentanil treatment comprise the left dorsal horn (DH) and layer X (LX). Parameter estimates show that spinal activity in the DH is reduced during remifentanil treatment compared to saline. Region of interest (ROI)-masked statistical t-maps are overlaid on an average mean echo planar imaging (EPI) image in PAM50 template space and the visualization threshold is set to p_corr<0.05, which is indicated as a dashed line in the color bar. The dashed circle indicates the cluster from which peak voxel parameter estimates are plotted. Error bars represent standard error of the mean.