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. Author manuscript; available in PMC: 2022 Apr 26.
Published in final edited form as: Nat Biotechnol. 2020 Dec 3;38(12):1421–1430. doi: 10.1038/s41587-020-00763-w

Extended Data Fig. 4. Characterization of hStrS.

Extended Data Fig. 4

(a) VoxHunt mapping of the hStrS GABAergic neuron cluster to the BrainSpan human brain dataset (PCW 5–10, 10–15, and 15–20). (b) VoxHunt mapping of the glutamatergic neuronal cluster in hStrS. (c) Expression of early amygdala marker TFAP2D in hStrS. (d) UMAP visualization of single cell RNA expression in GABAergic neurons subcluster of hStrS at day 80–83 of in vitro differentiation. (e) Expression of SST, PVALB, CALB1, CALB2, CHAT, TH, NOS1, NPY in the hStrS GABAergic subcluster. (f) Left, immunostaining for MAP2 (green), CALB1 (magenta), Hoechst (blue) in hStrS at day 85. Right, immunostaining for MAP2 (green), CALB2 (magenta), Hoechst (blue) in hStrS at day 85. n = 4 hiPS cell lines. Scale bar: 50 μm.