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. Author manuscript; available in PMC: 2022 Apr 26.
Published in final edited form as: Cell Rep. 2022 Mar 29;38(13):110569. doi: 10.1016/j.celrep.2022.110569

KEY RESOURCES TABLE.

REAGENT or RESOURCE SOURCE IDENTIFIER
Deposited data
TCGA: Copy Number PanCanAtlas: https://gdc.cancer.gov/about-data/publications/pancanatlas broad.mit.edu_PANCAN_Genome_Wide_SNP_6_whitelisted.seg
TCGA: Methylation PanCanAtlas: https://gdc.cancer.gov/about-data/publications/pancanatlas usc.edu_PANCAN_merged_HumanMethylation27_HumanMethylation450.betaValue_whitelisted.tsv
TCGA: Mutation PanCanAtlas: https://gdc.cancer.gov/about-data/publications/pancanatlas mc3.v0.2.8.PUBLIC.maf.gz
TCGA: Gene expression PanCanAtlas: https://gdc.cancer.gov/about-data/publications/pancanatlas EBPlusPlusAdjustPANCAN_IlluminaHiSeq_RNASeqV2.geneExp.tsv
TCGA: miRNA expression PanCanAtlas: https://gdc.cancer.gov/about-data/publications/pancanatlas pancanMiRs_EBadjOnProtocol PlatformWithoutRepsWithUnCorrectMiRs_08_04_16.csv
TCGA: Protein expression PanCanAtlas: https://gdc.cancer.gov/about-data/publications/pancanatlas TCGA-RPPA-pancan-clean.txt
TCGA: Clinical data PanCanAtlas: https://gdc.cancer.gov/about-data/publications/pancanatlas TCGA-CDR-SupplementalTableS1.xlsx
Software and algorithms
GraphPad Prism https://www.graphpad.com/ RRID:SCR_002798
NetworkX https://networkx.org/ RRID:SCR_016864
STRING DB https://string-db.org/ RRID:SCR_005223
SciPy https://scipy.org/ RRID:SCR_008058
Pandas https://pandas.pydata.org/ V1.2.4
Other
Recurrently-mutated driver genes Bailey et al., Cell 2018 Table S1
FDA-approved cancer therapies National Cancer Institute https://www.cancer.gov/about-cancer/treatment/drugs
NCI60 cell line doubling times CellMiner https://discover.nci.nih.gov/cellminer/celllineMetadata.do
Suz12 binding sites Lee et al., Cell 2006 Table S9
Cancer gene dependency scores http://www.depmap.org DepMap Public 21Q2