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Susceptibilities of spontaneous Ro 66-6976-resistant mutants compared to that of the E. coli wild-type strain for two PDF inhibitors and two unrelated antibiotics
| Strain | MIC (μg/ml)b
|
|||
|---|---|---|---|---|
| Ro 66-6976 | Ro 66-0376 | Erythromycin | Trimethoprim | |
| XL2 (wt)a | 8 | 32 | 32 | 0.5 |
| XL2-66-6976-1 | >128 | >128 | 16 | 0.5 |
| XL2-66-6976-2 | >128 | >128 | 16 | 1 |
wt, wild type.
Determined after 24 (wild-type strain) and 72 (mutants) h.
