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. 2022 Apr 27;12(4):220004. doi: 10.1098/rsob.220004

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© 2022 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 5. — Dysregulated Notch signalling in vascular disease. Left: Diseases linked to mutations or aberrant regulation of NOTCH3. Right: Diseases linked to mutations or aberrant regulation of other genes in the Notch signalling pathway. CCM, cerebral cavernous malformation; VHL, von Hippel–Lindau.