Table 4.
Ratio of associations between risk factors and cardiovascular disease among South Asian and Black participants relative to White
South Asian | Black | |||
---|---|---|---|---|
HR ratio (95% CI) | P | HR ratio (95% CI) | P | |
Deprivation indexa | 0.95 (0.89, 1.00) | 0.13 | 0.98 (0.91, 1.06) | 0.69 |
Physical activity levelb | 0.88 (0.81, 0.97) | 0.01 | 0.90 (0.80, 1.01) | 0.07 |
TV viewingb | 0.95 (0.89, 1.01) | 0.12 | 0.93 (0.86, 1.00) | 0.12 |
Dietary intakeb | ||||
Fruit and vegetable | 1.00 (0.95, 1.05) | 0.96 | 1.08 (1.01, 1.15) | 0.06 |
Red meat | 0.98 (0.92, 1.03) | 0.41 | 0.94 (0.88, 1.00) | 0.14 |
Processed meat | 0.96 (0.82, 1.14) | 1.00 | 0.96 (0.78, 1.19) | 1.00 |
Low oily fish | 1.02 (0.89, 1.17) | 1.00 | 0.88 (0.58, 1.33) | 1.00 |
Smoking statusb | ||||
Never | 1 (Reference) | 1 (Reference) | ||
Former | 0.80 (0.67, 0.96) | 0.053 | 1.11 (0.89, 1.39) | 0.34 |
Current | 0.62 (0.51, 0.77) | <0.0001 | 0.76 (0.58, 0.98) | 0.07 |
Alcohol drinkingb | 0.96 (0.88, 1.05) | 0.36 | 0.90 (0.80, 1.02) | 0.23 |
Adiposityc | ||||
BMI | 1.16 (1.08, 1.24) | <0.0001 | 1.08 (1.00, 1.17) | 0.06 |
Waist-hip ratio | 1.08 (1.01, 1.16) | 0.07 | 1.00 (0.90, 1.11) | 0.95 |
Physiological factorsd | ||||
Grip strength | 1.04 (0.96, 1.12) | 0.70 | 0.98 (0.89, 1.10) | 0.77 |
Systolic blood pressure | 0.99 (0.93, 1.07) | 1.00 | 1.01 (0.91, 1.12) | 1.00 |
Serum-based biomarkersd | ||||
LDL-c | 1.01 (0.94, 1.08) | 0.78 | 0.95 (0.86, 1.06) | 0.72 |
Triglycerides | 1.08 (1.02, 1.14) | 0.01 | 1.03 (0.91–1.17) | 0.68 |
HbA1c | 1.05 (1.01, 1.09) | 0.04 | 1.03 (0.96, 1.09) | 0.42 |
Cystatin C | 1.00 (0.94, 1.06) | 0.91 | 1.13 (1.04, 1.23) | 0.01 |
GGT | 1.04 (0.97, 1.10) | 0.37 | 0.94 (0.85, 1.03) | 0.37 |
HR ratios are the interaction terms HRSouth Asian:HRWhite and HRBlack:HRWhite
CVD cardiovascular disease, HR hazard ratio, CI confidence interval, BMI body mass index, LDL-c low-density lipoprotein cholesterol, HbA1c glycated haemoglobin, GGT gamma-glutamyl transferase
aModel 1: adjusted for age and sex only
bModel 2: additionally adjusted for deprivation
cModel 3: additionally adjusted for lifestyle factors
dModel 4: additionally adjusted for adiposity markers