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. 2021 Dec 8;102(5):485–493. doi: 10.1038/s41374-021-00710-6

Fig. 5. Reconstitution of miR-200c in Mir200c−/− mice prevents the progression of cholestatic liver fibrosis.

Fig. 5

A Representative images of H&E and Masson Trichrome staining of liver sections. Mir200c−/− mice were transduced with AAV8-con (control) or AAV8-miR-200c (overexpression) viruses via tail vein injection for one month, followed by sham or BDL for 1 week (n = 5 mice/group). B, C, and D Levels of ALT, AST, TBIL, DBIL, and BAs in the serum (B), as well as qPCR of gene expression (C) and WB of protein expression (D) in the livers of mice from (A). All data are shown as mean ± SEM (n = 5 mice/group). *P < 0.05 &**P < 0.01 vs. AAV8-con.