Table 1.
Patients’ demographic characteristics and immunosuppression regimen.
| Vaccinated patients (n = 82) |
Control group (n = 82) |
p-value | |
|---|---|---|---|
| Age (year) | 45 (38–63) | 47 (39–60) | 0.588 |
| Sex | |||
| Male | 41 (50) | 41 (50) | 1 |
| Female | 41 (50) | 41 (50) | |
| Duration from tx to COVID-19 (months) | 113 (36–174) | 106 (36–171) | 0.844 |
| Time from vaccination to COVID-19 (months) | 114 (78–158) | ||
| Etiology of CKD | 0.200 | ||
| Hypertensive nephropathy | 8 (9.8) | 5 (6.1) | |
| Diabetic nephropathy | 8 (9.8) | 12 (14.6) | |
| Chronic glomerulonephritis | 11 (13.4) | 12 (14.6) | |
| CAKUT | 13 (15.9) | 20 (24.4) | |
| Other | 14 (17.1) | 5 (6.1) | |
| Unknown | 28 (34.1) | 28 (34.1) | |
| Comorbid diseases | |||
| Pre-existing lung disease | 1 (1.2) | 5 (6.1) | 0.096 |
| Previous heart disease | 13 (15.9) | 10 (12.2) | 0.460 |
| Chronic hypertension | 43 (52.4) | 60 (73.2) | 0.010 |
| Post-transplant diabetes mellitus | 16 (19.5) | 14 (17.1) | 0.714 |
| Type of donor | |||
| Living | 63 (76.8) | 63 (76.8) | 1 |
| Cadaver | 19 (23.2) | 19 (23.2) | |
|
Induction therapy ATLG |
45 (54.9) |
48 (58.5) |
0.636 |
| Posttransplant complications | 7 (8.5) | 11 (13.4) | 0.304 |
| Allograft rejection | 2 (2.4) | 2 (2.4) | 1 |
| BK virus nephropathy CMV viremia |
0 | 0 | |
| Maintenance immunosuppression at admission | |||
| Tacrolimus | 63 (76.8) | 68 (82.9) | 0.330 |
| Cyclosporine A | 11 (13.4) | 8 (9.8) | 0.464 |
| Everolimus | 4 (4.9) | 5 (6.1) | 0.731 |
| Sirolimus | 1 (1.2) | 2 (2.4) | 0.271 |
| Mycophenolate derivatives | 70 (85.4) | 73 (89) | 0.483 |
| Azathioprine | 8 (9.8) | 3 (3.7) | 0.129 |
| Steroids | 77 (93.9) | 81 (98.8) | 0.210 |
Abbreviations: ATLG: anti-T-lymphocyte globulin; CAKUT: congenital abnormalities of the urinary tract; CKD: chronic kidney disease; CMV: cytomegalovirus; tx: transplantation.
P-values compared vaccinated patients and control group, obtained from the Chi-Square test, Fisher’s exact test, or Mann–Whitney U test. Data were presented as n (%) or median [Interquartile range 25–75] unless otherwise noted. Bold indicates statistically significant associations (p < 0.05).