Table 3.
Vaccinated patients (n = 82) |
Control group (n = 82) |
p-value | |
---|---|---|---|
Duration of hospitalization (days) | 8 (5–12) | 11 (7–21) | <0.001 |
Follow-up after COVID-19 | 57 (32–81) | 134 (104–203) | 0.812 |
Vaccine Regimens | |||
Two doses of CoronoVac | 21 (25.6) | ||
Two doses of BNT162b2 | 20 (24.4) | ||
Three doses of CoronoVac | 14 (17.1) | ||
Two doses of CoronoVac and one of BNT162b2 | 27 (32.9) | ||
Withdrawal of IS agent | |||
Calcineurin inhibitors | 9 (11) | 10 (12.2) | 0.807 |
Antimetabolites | 66 (80.5) | 69 (84.1) | 0.539 |
Treatment of infection | |||
Hydroxychloroquine | 0 | 17 (20.7) | <0.001 |
Favipiravir | 60 (73.1) | 64 (78) | 0.467 |
Cytokine‐targeted therapy | 4 (4.9) | 6 (7.3) | 0.514 |
Anakinra | 3 (3.7) | 4 (4.9) | 0.699 |
Tocilizumab | 1 (1.2) | 2 (2.4) | 0.560 |
Anticoagulation | 17 (20.7) | 34 (41.5) | 0.004 |
Antibiotics | 18 (22.5) | 38 (46.3) | <0.001 |
Ventilation devices | |||
Nasal cannula | 9 (11) | 20 (24.3) | 0.244 |
Non-invasive ventilation | 4 (4.9) | 8 (9.8) | 0.230 |
Mechanical ventilation | 5 (6.1) | 10 (12.2) | 0.168 |
Acute kidney injury | 13 (15.9) | 20 (24.4) | 0.160 |
Stage 1 | 9 (11) | 7 (8.8) | 0.599 |
Stage 2 | 3 (3.7) | 6 (7.3) | 0.495 |
Stage 3 | 1 (1.2) | 7 (8.5) | 0.029 |
Endpoints | |||
Cytokine storm | 4 (4.9) | 11 (13.4) | 0.061 |
ARDS | 5 (6.1) | 10 (12.2) | 0.168 |
Hospitalized patient | 17 (20.7) | 34 (41.5) | 0.004 |
Follow-up in ICU | 5 (6.1) | 10 (12.2) | 0.168 |
Death | 4 (4.9) | 9 (11) | 0.247 |
Abbreviations; IS: immunosuppression; IVIG: intravenous immunoglobulin; ARDS: acute respiratory distress syndrome; ICU: intensive care unit.
P-values compared vaccinated patients and control group obtained from the Chi-Square test, Fisher’s exact test, or Mann–Whitney U test. Data were presented as n (%) or median [Interquartile range 25–75] unless otherwise noted. Bold indicates statistically significant associations (p < 0.05).