Cytotoxic and antiviral activity of compound 5a on the Vero cells against VV, HSV-1, and on the CCV cells against BDV^a.

CC50, μM	IC50, μM	SIBOB	IC50, μM	SIHSV-1	CC50, μM	IC50, μM	SIVDC
Vero	VV		HSV-1		CCV	BDV
298 ± 50	103 ± 10	2.9	Inactive	—	298 ± 50	46.88 ± 2	6.4

^aCC₅₀ – 50% cytotoxic concentration, the concentration resulting in death of 50% of cells in culture; IC₅₀ – 50% inhibiting concentration, the concentration resulting in a 50% decrease of the virus production as compared to control; SI – selectivity index.