Skip to main content
. 2021 Oct 26;11(55):34688–34698. doi: 10.1039/d1ra06030a

Molecular mechanisms of metal-based nanoparticle antibacterial activity.

NPs Molecular mechanisms Ref.
Ag Inhibiting DNA replication, damaging the cell membrane, and inactivation of proteins 38
Ag Affecting the purine metabolite pathway is another antibacterial mechanism 39
Ag Makes penetration through cell membrane easier, cooperating with intracellular materials and allowing cell destruction 41
TiO2/ZnO Reactive oxygen species (ROS) aid as cell signaling molecules for regular biological processes and damage many cellular and molecular processes 42
C-based Mechanical damage or apply oxidant 43
AuNPs AuNPs target the energy metabolism and transcription process of bacteria 26
AuNPs Formation of IB-AuNPs, and disruption of the bacterial cell membrane 48