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. 2021 Oct 28;11(55):35011–35019. doi: 10.1039/d1ra06182h

Cytotoxic (IC50 in μM) activities of compounds 1–2, 4–6.

Compound 1 2 4 5 6 Adriamycin
BGC-823 89.5 ± 6.6 >100 36.7 ± 3.5 40.4 ± 5.2 >100 1.5 ± 0.1
H460 66.8 ± 3.4 75.6 ± 5.7 20.2 ± 1.6 34.8 ± 2.4 >100 1.0 ± 0.2
MDA-MB-231 80.2 ± 6.3 >100 10.6 ± 1.7 28.3 ± 2.3 >100 2.0 ± 0.4
SMMC7721 62.3 ± 4.5 78.1 ± 10.2 27.3 ± 2.1 43.2 ± 4.7 >100 2.2 ± 0.3