TABLE 1.

General and baseline features of patients enrolled

Characteristica	G-CSF group (n = 20)	Control group (n = 20)	P
No. of males/no. of females	16/4	14/6
Mean age (yr [range])	56.6 ± 8.6 (42–74)	59.8 ± 9.6 (44–85)	0.27
Mean duration of diabetes (yr [range])	15.6 ± 8.6 (1–46)	18.5 ± 8.6 (12–30)	0.22
No. (%) of patients with:
Wagner grade 3	13 (65)	14 (70)	0.12
Wagner grade 4	7 (35)	6 (30)	0.12
No. (%) of patients with the following type of lesion:
Neuropathic	13 (65)	14 (70)	0.12
Ischemic	2 (10)	0	0.31
Mixed	5 (25)	6 (30)
Mean ± SD ABI	0.96 ± 0.34	1.29 ± 0.50	0.04b
Mean ± SD VPT	35.8 ± 14.6	43.2 ± 0.47	0.19
No. of patients with WBC count >10,000/mm3	1	5	0.08
Mean ± SD neutrophil count/mm3	7,800 ± 3,500	8,300 ± 3,500	0.21
No. of patients with ESR >70 mm/h	11	13	0.52
No. of patients with positive blood cultures	0	2	0.15
No. (%) of patients with osteomyelitis	20 (100)	20 (100)	0.16
No. of patients with life-threatening infection	0	2	0.15

^aABI, ankle/brachial blood-pressure index; VPT, vibrator perception threshold; WBC, leukocyte; ESR, erythrocyte sedimentation rate. 

^bNot relevant, since all values were >0.8.