Key clinical trials of daridorexant (Idorsia Pharmaceuticals)

Drug(s)	Indication	Phase	Status	Location(s)	Identifier
Daridorexant, Placebo	Insomnia disorder	III	Recruiting	Japan	jRCT2031200452
Daridorexant	Insomnia disorder	III	Recruiting	Japan	JapicCTI-205444
Daridorexant, famotidine, efavirenz	Drug-drug interactions in volunteers	I	Completed	Germany	NCT04390334
Daridorexant, moxifloxacin, placebo	Thorough QT study in volunteers	I	Completed	Czech Republic	NCT04250506
Daridorexant	Renal impairment	I	Completed	Germany	NCT04024332
Daridorexant, citalopram, placebo	Drug-drug interactions in volunteers	I	Completed	Germany	NCT03907215
Daridorexant, zopiclone, placebo	Driving performance in volunteers	I	Completed	Netherlands	NCT03892902
Daridorexant, placebo	Effects on respiration in patients with obstructive sleep apnoea	I	Completed	Germany	NCT03765294
Daridorexant	Effects of food on pharmacokinetics in volunteers	I	Completed	Czech Republic	NCT03799978
Daridorexant, placebo	Effects on respiration in patients with chronic obstructive pulmonary disease	I	Completed	Germany	NCT03646864
Daridorexant, placebo	Insomnia disorder	III	Completed	Multinational	NCT03679884
Daridorexant, suvorexant, zolpidem, placebo	Abuse potential in healthy recreational drug users	I	Completed	USA	NCT03657355
Daridorexant, ethanol, placebo	Drug-drug interactions in volunteers	I	Completed	Netherlands	NCT03609775
Daridorexant, placebo	Insomnia disorder	III	Completed	Multinational	NCT03545191
Daridorexant, placebo	Insomnia disorder	III	Completed	Multinational	NCT03575104
Daridorexant	Hepatic impairment	I	Completed	Switzerland	NCT03713242
Daridorexant, rosuvastatin	Drug-drug interactions in volunteers	I	Completed	Czech Republic	NCT03339752
Daridorexant, placebo	Ethnic sensitivity study in Japanese vs Caucasian volunteers	I	Completed	Netherlands	NCT03101189
Daridorexant, midazolam	Drug-drug interactions in volunteers	I	Completed	Germany	NCT03017495
Daridorexant, placebo	Insomnia disorder	II	Completed	USA, Germany	NCT02841709
Daridorexant, zolpidem, placebo	Insomnia disorder	II	Completed	Multinational	NCT02839200
Daridorexant, placebo	Multiple ascending dose study in volunteers	I	Completed	Netherlands	NCT02571855
Daridorexant, diltiazem	Drug-drug interactions in volunteers	I	Completed	Germany	NCT02526888
Daridorexant, 14C-labeled daridorexant microtracer, placebo microtracer	Single ascending dose study in volunteers	I	Completed	Netherlands	NCT02919319