Table 2.
Relative gene expression, percentage of αSMA positives cells and synovial thickness in inflamed mouse synovial membranes where Cemip expression was silenced (CIOA shCemip) or not (CIOA shNT)
| Relative gene expression | % αSMA positives cells | Synovial thickness (vm) | ||||
|---|---|---|---|---|---|---|
| Cemip | Il1b | Il6 | Acta2 | |||
| CIOA shNT |
0.2082 ± 0.2459 (0.0410–0.7680) |
0.1246 ± 0.1890 (0.0030–0.5160) |
0.0586 ± 0.0684 (0.0020–0.1710) |
0.1005 ± 0.1796 (0.0040–0.5070) |
88.49 ± 11.05 (70.07–98.01) |
372.8 ± 62.33 (322–482) |
| CIOA shCemip |
0.0714 ± 0.0498 (0.0190–0.1640) |
0.0581 ± 0.0970 (0.0001–0.2360) |
0.0062 ± 0.0081 (0.0010–0.0200) |
0.0280 ± 0.0381 (0.0051–0.0100) |
63.18 ± 8.430 (52.57–74.59) |
248.3 ± 96.96 (115–368) |
| n | 9 | 7 | 6 | 9 | 7 | 7 |
| κ |
0.6 (0.34–1.54) |
0.4 (0.65–1.45) |
0.7 (0.4–1.86) |
0.5 (0.43–1.43) |
2.7 (1.25–4.14) |
0.9 (0,20–2) |
Values are presented as mean ± standard deviation, with range in brackets. κ (Cohen coefficient) with 95% CI in brackets define the effect size as follow: very small (0.01); small (0.2); medium (0.5); large (0.8); very large (1.2) and huge (2)