Table 1.

Studies Comparing the Treatment Outcomes of Daptomycin Versus Vancomycin or Ceftaroline for Methicillin-Resistant Staphylococcus aureus Bacteremia^a

Study	Design	No. of Patients	Treatment	Outcome
Zasowski et al, 2021 [18]	Retrospective cohort	278	DAP vs CPTb	10.7% vs 14.5% 30-d all-cause mortality
Schweizer et al, 2021 [15]	Retrospective cohort	108	VAN vs switching to DAPc within 3 d	17.4% vs 8.3% 30-d all-cause mortality
Claeys et al, 2016 [14]	Retrospective cohort	262	VAN vs DAPd	15.3% vs 6.1% 30-d all-cause mortality
Murray et al, 2013 [16]	Retrospective cohort	170	VAN vs DAPe	12.9% vs 3.5% 30-d mortality
Fowler et al, 2006 [13]	RCT	124	VAN + GEN vs DAPf	10.8% vs 11.3% mortality at 42-d follow-up

Abbreviation: CPT, ceftaroline; DAP, daptomycin; GEN, gentamicin; RCT, randomized controlled trial; VAN, vancomycin.

Studies include only adult patients.

Median DAP dose: 7.7 mg/kg total body weight (8.5 mg/kg adjusted body weight).

Ninety-three percent of patients received DAP ≥5 mg/kg.

Median DAP dose: 8.2 mg/kg total body weight.

Median DAP dose: 8.4 mg/kg.

DAP dose: 6 mg/kg.