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. 2022 Apr 22;17:1803–1827. doi: 10.2147/IJN.S353349

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© 2022 Porrang et al.

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(A) Schematic illustration of MSN-BM/CD-HApt@DOX synthesis process and (B) the mechanism of targeting and cancer cells apoptosis.

Note: Reproduced from Shen Y, Li M, Liu T, et al.A dual-functional HER2 aptamer-conjugated, pH-activated mesoporous silica nanocarrier-based drug delivery system provides in vitro synergistic cytotoxicity in HER2-positive breast cancer cells. Int J Nanomedicine. 2019;14:4029-4044. Originally published by and used with permission from Dove Medical Press Ltd.¹⁴⁰