TABLE 1.
Sources and characteristics of trimethoprim-resistant and -susceptible S. pneumoniae isolates
| Isolate | Sourcea | Serotypeb | MIC (mg/liter)
|
|
|---|---|---|---|---|
| Sulfamethoxazole | Trimethoprim | |||
| Pn94/720c | CSF | 23F | 512 | 256 |
| Pn93/1293d | Blood culture | 6B | 512 | 256 |
| Pn93/1802e | Blood culture | 9V | 256 | 256 |
| P48 | Unknown | ND | 1,024 | 256 |
| R12 | Sputum | ND | 256 | 512 |
| Pn93/1791 | Blood culture | 19F | 16 | 4 |
| Pn93/917 | CSF | 9V | 32 | 8 |
| Pn93/908 | CSF | 14 | 32 | 4 |
| Pn94/258 | Blood culture | 23F | 32 | 4 |
| CP1015 | — | 64 | 4 | |
| ATCC 49619 | — | 64 | 4 | |
a
CSF, cerebrospinal fluid.
b
ND, not done; —, nonencapsulated.
c
“Spanish” 23F multiresistant clone.
d
“Spanish” 6B multiresistant clone.
e
“French/Spanish” 9V multiresistant clone.