Skip to main content
. 2022 Apr 13;13:851680. doi: 10.3389/fphar.2022.851680

FIGURE 3.

FIGURE 3

Ferroptosis inhibitors including liproxstatin-1 and UAMC 3203 reversed the effect of FZKA. A, PC9 cells were treated as (A) FZKA (1.5 mg/ml), UAMC3203 (25 nM) or liproxstatin-1 (200 nM) for 24 h, and stained with BODIPY™ 581/591 C11 (10 μM) for 30 min. The level of lipid peroxidation was detected by flow cytometry. Each point represents the mean ± SEM, n = 3, *p <0.05. (B), Cultured NSCLC cells were seeded in 96 well plate, FZKA (1.5 mg/ml in A549 and PC9 cells, 1 mg/ml in H1650 and H1299 cells), with UAMC3203 (25 nM), or liproxstatin-1 (200 nM) for 24 h. Cell viability was detected by CCK-8 assay, *p < 0.05.