FIGURE 6.

Overexpression of GPX4 reversed the efficacy of FZKA. (A), Cultured H1299 and PC9 cells were transfected with negative control and GPX4 lentiviral vectors, then treated with or without FZKA for 24 h. The expression of GPX4 was detected by western blot. (B), lipid peroxidation assay was performed in A549 cell after treatment with FZKA or/and GPX4 lentivirus. (C), Cells were transfected and treated with FZKA, and CCK-8 assay were then conducted. Each point represents the mean ± SEM, n = 3. *p < 0.05.