TABLE 1.
miRNAs and their target genes involved in inflammation and fibrosis post-MI.
| miRNA | Target gene(s) | References |
| Inflammation | ||
| miR-19a/b | Bim1/PTEN | (8) |
| miR-21 | KBTBD7/NF-κB | (9) |
| miR-22 | VE-cadherin | (10) |
| miR-92a | JNK/ERK1/2 | (11) |
| miR-133a | VEGFR2 and FGFR1 | (12) |
| miR-144-3p | PI3K/Akt/VEGF | (13) |
| miR-144-3p | PTEN | (13, 14) |
| miR-146a-5p | TLR7 | (15) |
| miR-155 | SOCS1 | (16) |
| miR-320 | PI3K/Akt/VEGF | (13) |
| miR-375 | PDK-1/Akt | (17) |
| Fibrosis | ||
| miR-1 | Cyclin D2 and CDK6 | (18) |
| miR-1 | PTEN/Akt | (19) |
| miR-19b | PTEN | (20) |
| miR-21 | TGF-β1/SMAD7 | (21) |
| miR-21 | CADM1/STAT3 | (22) |
| miR-21 | Notch/Jagged1 | (23) |
| miR-22 | Osteoglycin/VSMC marker genes | (24) |
| miR-34a | SMAD4 | (25) |
| miR-92a | SMAD7 | (26) |
| miR-125b | p53/TGF-β1 | (27) |
| miR-126 | HIF-1α | (28, 29) |
| miR-130a | PTEN/Akt | (30) |
| miR-132 | FOXO3 and SERCA2a | (49) |
| miR-133a | GTP Cyclohydrolase 1 (GCH1) | (31, 32) |
| miR-144-3p | PTEN | (14) |
| miR-146b-5p | IRAK1 and CEACAM1 | (33) |
| miR-155 | Ang II | (34) |
| miR-195 | SMAD7 | (35) |
| miR-200a-3p | PIGF/VEGF-A | (36) |
| miR-214 | Mfn2 | (37) |
| miR-590-3p | ZEB1 | (38) |