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. 2022 Apr 26;7:48. doi: 10.1038/s41541-022-00466-0

Fig. 6. Pulmonary administration of KFE8-Ag85B or KFE8-Ag85B pulsed BMDCs does not significantly improve BCG-induced protection.

Fig. 6

a BCG-primed mice were given i.t. boosts four weeks later with either KFE8-Ag85B or KFE8-Ag85B pulsed DCs. An additional four weeks after boost, mice were challenged via an aerosol route with 100 CFU of Mtb H37Rv. b Eight weeks p.i. lungs were harvested, homogenized, and plated for CFU enumeration. Data shown as mean ± SE. Significance was determined by one-way ANOVA followed by a Benjamini Krieger Yekutieli post hoc test for multiple comparisons to determine differences due to treatment and among treatment groups. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.