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. 2021 Nov 3;11(56):35455–35462. doi: 10.1039/d1ra01737c

Iron contents (μg Fe per g tissue) in the left brain extracted from three groups of rats injected with PVP-SPIONs and DMPC/PVP-SPIONs after 24 h and 7 d.

Group CON PVP-SPIONs DMPC/PVP-SPIONs
Substantia nigra 24 h 115.7 ± 43.0 486.8 ± 52.0 298.0 ± 35.7
7 d 162.2 ± 62.7 133.8 ± 32.2
Temporal lobe 24 h 194.8 ± 31.8 225.8 ± 51.9 583.1 ± 48.0
7 d 269.1 ± 60.6 332.1 ± 39.9
Frontal cortex 24 h 128.2 ± 47.7 174.4 ± 41.3 294.0 ± 58.4
7 d 254.0 ± 41.1 198.9 ± 32.6