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. 2022 Jan 28;13(5):1510–1529. doi: 10.1016/j.jcmgh.2022.01.014

Figure 6.

Figure 6

Hepatic dysplasia is exhibited in OGT-KO mice 28 days after PHX.A, H&E representative photomicrographs of liver sections from control and OGT-KO mice 0 hours and 2, 7, and 14 days after PHX at 200× magnification. B, H&E staining of 28 days after PHX at 200× and 400× magnification with arrow heads indicating mitotic figures. # represents central vein and ∗ represents portal triad. C, qPCR analysis of Cyclin D1, A2, E1, and B1 in OGT-KO and control livers from mice 28 days post-PHX, normalized to 18S and median of the control. Western blot analysis of liver lysate from 28 days after PHX OGT-KO mice of cyclin D1, A1, E1, B1 (D), and PCNA (E) with their corresponding densitometry. Bars represents the mean ± standard deviation. ∗P < .05 and ∗∗P < .01.