Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
miRNAs control MLCK/p-MLC and Rho/ROCK/p-MLC signaling pathway in IBD. (A) miR-1, miR-185-3p, and miR-200b target and inhibit MLCK or p-MLC levels to block the recombination of TJ proteins, and possibly reverse the impaired intestinal barrier function in IBD. (B) miR-21, miR-31, and miR-199a-5p respectively target and downregulate RhoB, RhoA, and ROCK1 levels, and possibly inhibit the progress of IBD.
