. 2022 Apr 13;13:868229. doi: 10.3389/fimmu.2022.868229

Table 1.

miRNA biomarkers in IBD.

Sample types	Expression	miRNAs	References
UC vs. normal
Intestine biopsies	Increase	miR-15, miR-16, miR-19a, miR-21, miR-31, miR-31-3p, miR-101, miR-125b, miR-206, miR-223, miR-155, miR-594	(1, 7, 17, 21–24)
Intestine biopsies	Decrease	miR-141, miR-200b, miR-214-3p*, miR-429	(25, 26)
Feces	Increase	miR-16-5p, miR-21-5p, miR-223, miR-1246*	(27, 28)
Feces	Decrease	N/A
Peripheral blood	Increase	miR-16, miR-21, miR-28-5p, miR-106a, miR-151-5p, miR-155, miR-199a-5p, miR-362-3p	(29, 30)
Peripheral blood	Decrease	N/A
CD vs. Normal
Intestine biopsies	Increase	miR-16, miR-19a, miR-21, miR-30c, miR-101, miR-223, miR-130a, miR-146a, miR-155, miR-594	(1, 6, 7, 31)
Intestine biopsies	Decrease	miR-141, miR-200a, miR-200b, miR-200c, miR-429	(25)
Feces	Increase	miR-15a-5p, miR-16-5p, miR-24-3p, miR-27a-3p, miR-128-3p, miR-142-5p, miR-223-3p, miR-223-5p, miR-3074-5p	(27, 32)
Feces	Decrease	miR-10a-5p, miR-10b-5p, miR-141-3p, miR-192-5p, miR-200a-3p, miR-375, miR-378a-3p, and let-7g-5p*	(32)
Peripheral blood	Increase	miR-16, miR-21, miR-23a, miR-29a, miR-106a, miR-107, miR-126, miR-155, miR-191,* miR-199a-5p, miR-200c, miR-362-3p, miR-532-3p	(29, 33)
Peripheral blood	Decrease	N/A

^*Possible differential miRNAs between UC and CD.