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. 2022 Apr 13;13:853230. doi: 10.3389/fphar.2022.853230

TABLE 1.

Histology activity score for scoring lung sections.

Score Organ Degeneration; pulmonary Features
0 None
1 Mild Inflammatory Exudate; areas of patchy Edema with some sisordered structure
3 Moderate Alveolar thickening (25–50% Visualized Lung)
4 Severe Alveolar Congestion (>50% visualized lung); Cellular debris filling air space; complete Loss of Alveolar Structure
Inflammation
0 No inflammation
1 Mild inflammatory exudate
3 Moderate inflammatory exudate
4 Severe inflammatory exudate
Fibrosis/lesions
0 No fibrosis
1 Minimal architectural distortion; Alveoli partly enlarged but no fibrotic masses
3 Fibrosis with architectural distortion but preserved lung structure
4 Lung structure severely damaged; Alveolar septa nonexistent with complete obliteration with fibrotic masses
Total score 12