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. 2021 Nov 9;11(57):36105–36115. doi: 10.1039/d1ra03565g

ANOVA for response surface quadratic model.

Factors Statistics
Sum of squares df Mean square F-Value P-Value
Model 0.77 14 0.055 10.48 < 0.0001
A-IPTG concentration 0.0006 1 0.0006 0.11 0.7394
B-induced cell density 0.013 1 0.013 2.52 0.1333
C-induction temperature 0.001204 1 0.001204 0.23 0.638
D-induction culture time 0.017 1 0.017 3.27 0.0907
AB 0.0005063 1 0.0005063 0.097 0.7598
AC 0.0005063 1 0.0005063 0.097 0.7598
AD 0.0007563 1 0.0007563 0.14 0.7089
BC 0.021 1 0.021 4.03 0.0632
BD 0.0016 1 0.0016 0.31 0.5881
CD 0.001225 1 0.001225 0.23 0.6352
A2 0.3 1 0.3 57.97 < 0.0001
B2 0.28 1 0.28 53.37 < 0.0001
C2 0.24 1 0.24 46.22 < 0.0001
D2 0.18 1 0.18 35.26 < 0.0001
Residual 0.078 15 0.005223
Lack of fit 0.078 10 0.007834
Pure error 0 5 0
Cor total 0.84 29
R 2 = 0.9073 Adj R2 = 0.8207