Table 2.

Univariate and multivariate cow analysis of primary cohort.

	Univariate analysis		Multivariate analysis
	HR (95% CI)	p-value	HR (95% CI)	p-value
Age*	1.038 (1.027 – 1.358)	<0.001	1.011 (1.000 – 1.022)	0.043
Gender
Female	0.977 (0.789 – 1.120)	0.832
Male	Reference
Grade
GBM	2.955 (2.442 – 3.576)	<0.001	2.345 (1.914 – 2.873)	<0.001
LGG	Reference
IDH-1 R132H
Wild-type	3.000 (2.258 – 3.987)	<0.001	1.789 (1.318 – 2.429)	<0.001
Mutation	Reference
Inflammation nutrition score*	2.538 (1.910 – 3.366)	<0.001	1.731 (1.188 – 2.523)	0.004

^*Markers were regarded as continuous variable.