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. 2022 Apr 27;12:6848. doi: 10.1038/s41598-022-11035-9

Table 2.

Correlation between calendar year and ocular parameters.

Variable Linear regression Adjusted for age and sex
β p-value β p-value
Model 1: examination results
Tear break-up time (s) − 0.228 < 0.001* − 0.233 < 0.001*
Schirmer test (mm) 0.030 0.632 0.105 0.110
Tear strip meniscometry (mm) − 0.117 0.257 − 0.105 0.304
Corneal staining score 0.069 0.008* 0.066 0.011*
Model 2: symptoms
Dryness 0.020 0.435 0.027 0.290
Irritation 0.022 0.384 0.018 0.489
Pain 0.056 0.030* 0.067 0.010*
Fatigue − 0.024 0.357 − 0.019 0.452
Blurring 0.132 < 0.001* 0.120 < 0.001*
Photophobia 0.053 0.042* 0.056 0.031*

Calendar years 2015, 2016, and 2017 = 0, 2018 and 2019 = 1.