The influence of different catalysts for the preparation of quinazoline-2,4(1H,3H)-dionea.
Entry | Catalyst | Yieldb (%) |
---|---|---|
1 | DFNS | — |
2 | DFNS/cellulose | — |
3 | DFNS/cellulose-ZnO | 96 |
4 | Cellulose-ZnO | 98 |
Reaction conditions: substrate (1.0 mmol), isocyanide (1.0 mmol), catalyst (5 mg), Cs2CO3 (1.0 mmol), DMF (5 mL), 70 °C, CO2 balloon, 3 hours.
Isolated yield.