Summary of in vivo and in vitro studies of anthelmintic potential of C. procera.

Model	C. procera extract/dose	Compared with drug	Observation	Result	References
In vivo: sheep infected with mixed species of nematodes in vitro: Haemonchus contortus	Crude powder (CP), crude aqueous (CAE) and crude methanolic extracts (CME)	Levamisole	88.4%, 77.8% and 20.9% reduction in egg count percent for CAE, CP and CME respectively	Aqueous extract of C. procera has good anthelmintic potential	105
Earthworms	Aqueous extract of dry latex (5, 10, 50 and 100 mg mL−1) and fresh latex (1.45, 7.25, 29, 72.5 and 145 mg mL−1)	Piperazine	At 5 to 10 mg mL−1 concentration paralysis at 90 min, at 100 mg mL−1 death within 60 min. Fresh latex also showed dose-dependent paralysis	Latex showed wormicidal activity, hence can be used as an anthelmintic agent	106