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Pig models of neurodegenerative diseases
| Human disease | Gene | Modification | References |
|---|---|---|---|
| Alzheimer | APP695sw | Knock‐in | 50 |
| Alzheimer | PSEN1 MI46I | Mutation | 52 |
| Alzheimer | APP SW , PSEN1 MI46I | Mutation | 53 |
| Alzheimer | hAPP, hTau, hPS1 | Mutation | 54 |
| Huntington | HTT | Mutation | 61 |
| Huntington | HTT | Knock‐in | 62 |
| Parkinson | Parkin, DJ‐1 | Knockout | 57 |
| Parkinson | PARK2, DJ‐1, PINK1 | Knockout | 59 |
| Parkinson | SNCA | Knock‐in | 60 |
| Parkinson | PARK2, PINK1 | Knockout | 58 |
